Engineering the resulting functionalities of quantum nanomaterials has an immense potential to revolutionize both the way we think about fundamental material science as well as for technological applications in fields from nanoelectronics and nanophotonics to quantum communication and sensing. For example, with van der Waals materials one could design materials with a strong nonlinear optical response for nanophotonics, drive clean energy reactions by exploiting their unique surface properties, assemble solid-state quantum bits for quantum computers, implement new platforms for ultra-precise quantum sensors, and implement single-photon emitters for secure quantum communications.